I see his point, and feel no need to comment, or disagree. In short, he says-
To this day I have yet to see a Prezi presentation that would not have been better had the speaker used something else, including nothing at all. Many presentations would be better if the speaker just spoke, sans slides or any props at all.
Here’s the full post and do take time to read some of the rest of his blog, it’s really good. And here for more more from me on how you can speak ‘sans slides’ or Prezi.

Jim Harvey
Managing Director at The Message Business
Jim is the MD of The Message Business, a company which helps FTSE 100 companies to sell themselves, and their products better. Speech writer, Prezi trainer and designer, coach and consultant, Jim also finds time to be a proud father and husband.

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